One difficulty in extracting sequencing reads that correspond to mitochondrial DNA from mixed fragments of nuclear...

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Biology

One difficulty in extracting sequencing reads that correspond tomitochondrial DNA from mixed fragments of nuclear and mitochondrialDNA is the nuclear genome contains segments homologous to regionsof the mitochondrial genome called \"numts.\" Mammalian genomescontain 50-450 kb of numts (the human genome contains 1005 numts,averaging 446 bp).
Estimate the fraction of reads from fragments of mammoth DNAthat are likely to be numts. The mammoth genome is approximately4.7x10^9 bases in length.

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Background Next generation ultrasequencing technologies are starting to produce extensive quantities of data from entire human genome or exome sequences and therefore new software is needed to present and analyse this vast amount of information The 1000 Genomes project has recently released raw data for 629 complete genomes representing several human populations through their See Answer

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