Most drugs cannot be excreted unchanged by the body but have to go through the process...

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Biology

Most drugs cannot be excreted unchanged by the body but have togo through the process of drug metabolism. Drug metabolism enablesstructural change within the drug allowing for itsâ€™ eliminationfrom the body. Describe in detail the processes involved in drugmetabolism. Your answer should include the reactions of phase I andphase II metabolism, the control of expression of cytochrome P450sand detailed examples of these processes in drugs chosen byyou.

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Drug metabolism Whenever a drug is administered through the oral route it goes through the hepatic first pass route to the liver where the drug metabolism occurs More technically it is the modification of the parent drug compound in the liver of the organism to make it either more active or less active These modifications are done by special enzyme systems present in the liver Results of Drug metabolism a Some drugs can get inactivated conversion to inactivated metabolite examples Chloramphenicol b Some drugs can get See Answer

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