Methanol and ethanol are both oxidized by alcohol dehydrogenase (ADH). Methanol is poisonous because it is...

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Methanol and ethanol are both oxidized by alcohol dehydrogenase(ADH). Methanol is poisonous because it is oxidized by ADH to formthe highly toxic compound formaldehyde. The adult body has 40 L ofwater, throughout which these alcohols are rapidly and uniformlydistributed. The densities of both alcohols are 0.79 g/mL. The Kmof ADH for ethanol is 1.0x10-­‐3 M, and for methanol the Km is1.0x10-­‐2 M. The molecular mass of methanol is 32 g/mol and thatof ethanol is 46 g/mol. If an individual consumed 100 mL ofmethanol (a leathal amount), how much 100-­‐proof whiskey (50%ethanol by volume) must this person consume in order to reduce theactivity of ADH toward methanol to 5%? Assume the Ki for ethanol =Km.

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Step 1 Calculate the concentration of methanol Molarity moles of methanol volume of solution in L Moles mass molar mass Mass density x volume volume of methanol 100 mL mass of    See Answer
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