Mechanism of action- Describe the location, storage and release of histamine- List the types of histamine receptors...

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Medical Sciences

Mechanism of action-
Describe the location, storage and release of histamine-
List the types of histamine receptors and the second messengerstriggered by the activation of those receptors-
Explain the molecular mechanism of action of H1-receptorantagonists-
Explain the molecular mechanism of action of H2-receptorantagonists
Actions on organ systems-
Describe the pharmacological effects of H1-receptorantagonists.-
Describe the pharmacological effects of H2-receptorantagonists.
Pharmacokinetics-
Describe the metabolism and elimination of H1-receptorantagonists.-
Describe the metabolism and elimination of H2-receptorantagonists
Adverse effects, drug interactions and contraindications-
Describe the main adverse effects of H1 an H2 receptorantagonists.-
Describe the main contraindications of H1 an H2 receptorantagonists.

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3.6 Ratings (344 Votes)

1 Histamine is a cell derived chemical mediator of inflammation It is a vasoactive amine Histamine along with serotonin 5 hydroxytryptamine plays an important role in the early hours of inflammation Histamine is mostly present in the mast cells basophil cells Mechanism Of Action The mechanism of action of histamine depends on the type of receptor to which it binds Histamine binds to the various G protein coupled histamine receptors present on the cell surface There are four histamine receptors H1 H2 H3 See Answer

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