Mechanism of action-
Describe the location, storage and release of histamine-
List the types of histamine receptors and the second messengerstriggered by the activation of those receptors-
Explain the molecular mechanism of action of H1-receptorantagonists-
Explain the molecular mechanism of action of H2-receptorantagonists
Actions on organ systems-
Describe the pharmacological effects of H1-receptorantagonists.-
Describe the pharmacological effects of H2-receptorantagonists.
Pharmacokinetics-
Describe the metabolism and elimination of H1-receptorantagonists.-
Describe the metabolism and elimination of H2-receptorantagonists
Adverse effects, drug interactions and contraindications-
Describe the main adverse effects of H1 an H2 receptorantagonists.-
Describe the main contraindications of H1 an H2 receptorantagonists.