McArdle Disease (glycogen storage disease 5) is caused by mutations in the phosphorylase enzyme in muscle....

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McArdle Disease (glycogen storage disease 5) is caused bymutations in the phosphorylase enzyme in muscle. The symptoms aremuscle cramps, pain, and fatigue during strenuous exercise. Anischemic exercise test is often used as part of the diagnosticprocess. This test measures lactate in the blood but is not alwaysspecific for McArdle. Explain why lactate might be a gooddiagnostic measurement for this disease and how its production isregulated in muscle in a normal person versus a McArdle patient

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McArdle Disease is a rare abnormality where a person will not be able to break down glycogen stored in their muscle cells because of the absence of an enzyme myophosphorylase Lack of this enzyme will not let your muscles use stored gycogen Ischemic exercise test is used to diagnose McArdle See Answer

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