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Mapk pathway you make a variety of mutants and then express them in some stem...

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Mapk pathway you make a variety of mutants and then express them in some stem cells Remember that this pathway is involved in cell division signaling in these cells Determine whether you think the following mutations could lead to an over proliferate cell phenotype for those stem cells A MapKK has what we call a phosphomimetic mutation with a Serine Aspartic Acid mutation at the site phosphorylated by MapKKK If this works as intended this mutation causes MapKK to always exist in what would be the phosphorylated state

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