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Managerial accounting The grumbling had gone on for months. Managers kept complaining that their monthly charges for voice telecommunication services didn't reflect the amount actually consumed. Consequently, there was a movement to reinstate detailed billing to support the monthly charges and the process to implement an activity-based chargeback system was proceeding full steam ahead. Mike Burton, Manager of Accounting Policy at The Boeing Company, wasn't sure the new activity-based system was the answer. He recalled that four years earlier Boeing had abandoned a detailed activity-based chargeback system because too much detail was being provided and the cost associated with providing the detail wasn't justified. Although the consumption of voice telecommunication services had increased dramatically over the past four years, Mike wasn't sure whether the increase was due to the use of the simplified chargeback system or whether it was due to changes in technology.

31 What is the cause of Pott's disease?

32 One thing that often baffles me is that patients with systemic lupus erythematosus often suffer recurrent thrombosis due to lupus anticoagulants (antiphospholipid syndrome). How can an anticoagulant cause thrombosis?

33 Are elevated homocysteine levels an independent risk factor for progression of systemic lupus erythematosus (SLE)/scleroderma? Kindly suggest some references if possible.

34 1. What are the indicators of remission in systemic lupus erythematosus (SLE)? Is it the normalization of erythrocyte sedimentation rate (ESR) and the disappearance of antinuclear antibodies (ANA) and other antibodies, or is it clinical improvement? 2. During remission of SLE, do ewANA and other antibodies disappear?

35 When should the use of cyclophosphamide in systemic lupus erythematosus (SLE) be commenced? What is the correct and safe dosage of cyclophosphamide?

36 1. Given the benefits of dexamethasone, which lacks any mineralocorticoid activity, why is this not prescribed in your book for diseases that require long-term steroid therapy, such as systemic lupus erythematosus or giant cell arteritis? 2. Does dexamethasone have more serious adverse effects than prednisolone? Why is it not generally preferred?

37 Would an elevated C-reactive protein (CRP) level, in association with a high erythrocyte sedimentation rate (ESR) and in the absence of infection and serositis, exclude the diagnosis of systemic lupus erythematosus?

38 How do steroids precipitate a crisis in patients with systemic sclerosis?

39 Are neck and face muscles commonly affected in poly- and dermatomyositis? Does this differ from the muscles that are affected with myasthenia gravis?

40 1. In dermatomyositis, what is the shawl sign? 2. How frequently is dermatomyositis associated with Gottron's papules?

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