List the stabilizing forces at tertiary level of protein structure. An enzyme containing the amino aspartic...

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Chemistry

List the stabilizing forces at tertiary level of proteinstructure. An enzyme containing the amino aspartic acid(pK_a of the side chain = 3.65) and histidine(pK_a of the side chain= 6) in the active (catalytic )site has an optimal activity at a pH of 5.0. What is the majorstabilizing force at the catalytic site? Using structures and 1-3complete sentences, predict and explain what is expected to happento the activity if the pH is increased to 8.
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3.8 Ratings (387 Votes)

Hi The primary structure of peptides and proteins refers to the linear number and order of the amino acids present The convention for the designation of the order of amino acids is that the Nterminal end ie the end bearing the residue with the free amino group is to the left and the number 1 amino acid and the Cterminal end ie the end with the residue containing a free carboxyl group is to the right In this peptide bonds are seen The ordered array of amino acids in a protein confer regular conformational forms upon that protein These conformations constitute the secondary structures of a protein In general proteins fold into two broad classes of See Answer

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