Let’s say the synapses of a neuron’s dendrites are filled with glutamate-gated channels which, when activated...

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Let’s say the synapses of a neuron’s dendrites are filled withglutamate-gated channels which, when activated by glutamate, causean excitatory postsynaptic potential (EPSP) in the neuron. In oneinstance, glutamate is released at all of the synapsessimultaneously and this leads to an action potential in theneuron.

A) What type of summation of PSPs is this? Why?

B) List the sequence of steps that occur starting from bindingof glutamate to the glutamate-gated channels at the synapses andending with the membrane potential at the axon hillock returning toresting potential at the end of the action potential. (Include allthe changes in voltage-gated channels underlying the actionpotential.)

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3.8 Ratings (718 Votes)
A If the neurotransmitter is excitatory and causes depolarization of the postsynaptic membrane then EPSP excitatory postsynaptic potential is generated Or if the released neurotransmitter is inhibitory and    See Answer
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