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JT is a 20 year old female on a continuous infusion of an antibiotic. The total...

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Medical Sciences

JT is a 20 year old female on a continuous infusion of anantibiotic. The total dose that will be given is 1500 mg over 24hours. The volume of distribution is 69 L and the drug half life is6.7 hours. What is the plasma drug concentration if a blood sampleis taken 29 hours after the infusion began? Note: Please provideyour answer in units of mg/L.

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3.8 Ratings (749 Votes)

A= C. Vd

here A= amount of the drug in the body

C = plasma concentration

Vd = volume of distribution of drug

1500mg= C. 69L

C= 1500mg/69L

C= 21.73mg/L

therefore plasma drug concentration in blood = 21.7mg/L
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