It is known that glucose entering the blood from the digestivetract causes a more significant increase in the insulin content inthe blood compared to the same amount of glucose, but administeredintravenously. Explain this phenomenon, taking into account theresults of the synthesis and secretion of insulin by beta-cells ofthe pancreatic islets of Langerhans.
For the answer:
1. Write the name of the molecules involved in regulating thesecretion of insulin betta by the cells of the pancreas
2. describe the steps in the synthesis and secretion of insulin andthe role of glucose in this process;
3. indicate which transmembrane mechanisms are used by the Gastricinhibitory polypeptide, the Glucagon-like peptide, which aresecreted by the cells of the small intestine mucous membrane whencarbohydrates and Cholecystokinin enter them to transmit signals tobeta cells
4. why the effect of the Gastric inhibitory polypeptide and theglucagon-like peptide on beta cells appears earlier than the effectof the main activator of insulin secretion - glucose.
