It has been demonstrated that some people treated with statinsshow an increased accumulation of lipids in theliver and skeletal muscles, aswell as a mitochondrial dysfunction in skeletalmuscles. Explain why statin treatmentresults in lipid accumulation in the liver and in theskeletal muscle.
What other metabolite accumulates explaining why there isincreased fatty acid synthesis if HMG-CoA (due to statin treatment)accumulates in the cytosol and slows downs the cholesterolsynthesis pathway.
