Indicate whether each of the following statements (a-e) is TRUE or FALSE.  If you think a statement...

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Biology

Indicate whether each of the following statements (a-e) is TRUEor FALSE.  If you think a statement is FALSE, explainwhy. (10 pts)

a.  TRUE / FALSE  Graft rejection ismediated by pre-existing host T cell effectors and antibodiesspecific for antigens on the grafted tissue.

b.  TRUE / FALSE  Allogeneic grafts betweenindividuals with identical HLA genes will be accepted.

c.  TRUE / FALSE    Your parentsare generally going to be your best source of tissues if you need atransplant.

d.  TRUE / FALSE    Graftrejection only occurs when alloantigens from the grafted tissue arepicked-up by recipient APCs and presented to recipient T cells.

e. TRUE / FALSE   In Graft Versus Host Disease(GVHD) innate cells from the grafted tissue recognize hostalloantigens and begin attacking host tissues.

Answer & Explanation Solved by verified expert
3.8 Ratings (558 Votes)
Graft rejection Graft rejection reflects the presence of immunocompetent cells in the host that specifically recognize and react to donorderived stem cells Several factors influence the likelihood of graft rejection in particular a the degree of immunocompetence of the host b the degree of HLA disparity between donor and recipient c the number and source of stem cells infused d the type of conditioning regimen used e the possible presensitization of the host to donor histocompatibility antigens and f the    See Answer
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