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In the intestine, bile acids binding to the FXR increase expression of target genes while in...

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Medical Sciences

In the intestine, bile acids binding to the FXR increaseexpression of target genes while in the liver target geneexpression is decreased. Describe the basis for these effects.

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Regulation of bile acid synthesis and effect in small intestine and liver after binding with FXR is established a crosstalk mechanism FXR is a tissue specific nuclear receptor found in both liver and small intestine showing differnt    See Answer
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