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In immunology: What do we mean by recognition of self vs. non-self? What specifically does “recognition” mean...

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Medical Sciences

In immunology:

  1. What do we mean by recognition of self vs. non-self? Whatspecifically does “recognition” mean in this context? What is themolecular nature of this interaction.
  2. What is immunological memory? Why does it matter, and whatspecifically does it allow for that has absolutely saved billionsof lives?
  3. Why is it useful to have two very different mechanisms ofantigen recognition (ie BCR vs TCR)? What problem might be morelikely to occur if all Ag were recognized the same way?

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4.1 Ratings (627 Votes)
1 Recognition of self vs nonself cells In the human body there are a large number of protein present which are divided into classes One such class is the MHC proteins also called as HLA antigens MHC Major Histocompatibility Complex proteins are synthesized by the MHC genes present in the chromosome 6 They help in differentiate between the self and nonself cells and helps in its recognition They are also known as Human Leukocyte antigens The self cells are the cells that body recognizes as a part of it The nonself cells are foreign cells which the body doesnt recognizes as its own Molecular nature of the interaction The MHC class of proteins are of two typs a MHC class I molecules They are found in all types of body cells b MHC class II molecules They are present in macrophages B lymphocytes    See Answer
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