If you wanted to conduct a case-control study to discover whether there was a relationship between...

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If you wanted to conduct a case-control study to discoverwhether there was a relationship between Parkinsonâ€™s disease andhaving worked in a high stress occupationâ€¦
A. How might you go about selecting the cases and the controlsfor this study?
B. Assume that after you have selected the cases and the controlyou have a total of 1,000 cases and 2,000 controls. You find thatamong the cases 200 worked in a stressful occupation and among thecontrols 390 worked in a stressful occupation. What would be theodds ratio describing the relationship between working in a highstress occupation and having Parkinsonâ€™s disease?
C. Interpret the meaning of this odds ratio.

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4.5 Ratings (852 Votes)

aThe purpose of the control group in a casecontrol study id toprovide information on the exposure distribution in the populationthat gave rise to the casesThus while selecting the cases I will prefer newly diagnosedcases because they tend to be more motivated to participate andmay remember relevant exposures more accurately and because itavoids complicating factors related to selection of longer See Answer

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