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If you made mice homozygous for loss-of-function mutations in Crx would you expect the level of...

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Biology

If you made mice homozygous for loss-of-functionmutations in Crx would you expect the level of GADD transcriptionto increase or decrease (relative to wildtype/normal)? Would GADDbe the only gene affected by the loss-of-function Crx mutation orwould the transcriptional levels of other genes change as well?Explain your answer.

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3.6 Ratings (440 Votes)
CRX gene codes for cone rod homeobox protein found in eye especially in light sensitive tissues like back of retina It works as transcriptional factor activating genes responsible for normal develoment    See Answer
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