If you cut parts off of the lead compound and it keeps
losing potency, what can...
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Biology
If you cut parts off of the lead compound and it keepslosing potency, what can you conclude? If that happens, what do youtry next?
And, You cut a piece off of the lead, and the potencydrops. When would it be beneficial to continue anyway with thistruncated lead?
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Lead compounds are the compounds having desired pharmacological activity These compounds have suboptimal structures and requires modification to enable the the compound to fit better with the receptor The part of the lead compound involved in binding with specific receptor using intermolecular interactions between the functional groups is called the pharmacophore The other regions
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