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I am testing the effects of a new drug, and find that liver cells treated with...

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Biology

I am testing the effects of a new drug, and find that livercells treated with this drug show the following effects:

-Reduced levels of AcCoA in the mitochondria

-Increased rates of gluconeogenesis

-Increased production of lactate

The drug, however, has no effect on Red Blood Cells (RBCs).

Why does the drug not have an effect on Red Blood Cells?What is the drug inhibiting/assisting? What other conclusions canbe made with this information? (Open ended question, there are nowrong answers!)

Answer & Explanation Solved by verified expert
3.7 Ratings (324 Votes)
I believe that the new drug is an inhibitor of Pyruvate Dehydrogenase PDH enzyme which catalyses the conversion of pyruvate to acetyl CoA It is a key enzyme in glucose metabolism connecting glycolysis with Krebs    See Answer
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