HUMAN GROWTH HORMONE 1. Describe the ligand and any external receptors that bind to the ligand. If...

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Biology

HUMAN GROWTH HORMONE
1. Describe the ligand and any external receptors that bind tothe ligand. If signaling can occur without an external ligand,explain how this can occur.
2. Describe how the signal is translocated from the exterior ofthe cell to the interior of the cell. Be sure to describe thespecific activity of the receptor in initiating the intracellularsignal.
3. Describe the propagation of the signal within the cell fromthe membrane receptor to the point of cellular response. Providethe details for at least one specific protein interaction thateither results in the activation or inactivation of a subsequentprotein or signaling molecule to propagate the signal.
4. What is a specific cellular response to the signal.Something will change- what is it?

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Please find the answers below Answer 1 When an extracellular signal molecule proximates the membrane bound receptor it gets bound to it by formation of chemical bonds As soon as the molecule binds to the ligand it causes a conformational change in the cytoplasmic domain of the receptor This conformational change then brings about a series of sequential cascade downstreams in the cytoplasm which cause activation of many See Answer

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