How were core promoter elements identified? How would you do this in a new organ

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Biology

How were core promoter elements identified?
How would you do this in a new organ

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Promoters are regulatory sequences in a genome which precede the 5 end of a protein coding region or exon and binds to the RNA polymerase enzyme which brings about transcription of the exon downstream of the promoter A promoter is very essential to be recognized by the RNA polymerase since prper recognition of promoters leads to the beginning of transcription in the transcription start sites TSS The core promoter is made up of promoter elements which include the polymerase binding site TSS and regulatory stretches of DNA that are essential for establishing trascription Therefore the core promoter elements are important components of the cell machinery and therefore needed to be identified and characterized In 1966 scientists Scaife and Beckwith hypothesized that it is possible that specific regions of the genome are responsible for carrying out gene expression They identified the role of mutations in altering the expression of genes which led to this See Answer

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