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How is glutamine used in nitrogen metabolism and Why is the activity of glutamine synthetase tightly...

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Biology

How is glutamine used in nitrogen metabolism and Why is theactivity of glutamine synthetase tightly regulated?

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Glutamine plays the a key role in the nitrogen N flow of organism it serve as both a N donor and nitrogen acceptor The enzymes glutamine synthetase GS is ubiquitous and found in all organisms and control conversion of ammonia into a amino acid glutamine In animal system GS is predominantly found in the liver brain and kidneys Along with glutamate glutamine maintains nitrogen homeostasis in Brain Within central nervous system    See Answer
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