How do the global and local reflexes address the optimization of the ventilation : perfusion ratio...

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Medical Sciences

How do the global and local reflexes address the optimization ofthe ventilation : perfusion ratio (keeping it close to 1)?

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Global lungventilationIn absence of any real scientific definition for this term onecould make something up for example it would be relatively easy tosay that global lung ventilation is the total volume of gas whichpasses through the lung per unit time Though one couldtheoretically pick some random arbitrary volume units and timeinterval the conventional way of expressing global lungventilation is as the minute volume Presumably for the purpose ofmaking subsequent calculations neater Nunnsgives4Lmin as the normal average minute volume whichcorresponds to a tidal volume of 400ml with a respiratory rate of10Regional variationin lungventilationThere are substantial differences in the rate of air supply todifferent parts of the lung This unequal distribution ofventilation is the consequence of several factorsThere is a gravityrelated vertical gradient of pleuralpressure which results in a difference in distending transpulmonarypressure during normal spontaneous ventilationPosture changes the See Answer

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