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How do Cells Attach to the ECM? Integrins: Apoptosis: What are triggers? What does this cause...

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Biology

How do Cells Attach to the ECM?

Integrins: Apoptosis: What are triggers? What does this cause incell? What is importance of location of PS (phosphatidyl serine) incell membrane? Caspases (role and examples of targets in cell)Apoptosome (look at role of cytochrome c)

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Cells attach to the underlying ECM extracellular matrix through integrindependent junctions called focal adhesions This attaches the actin cytoskeleton to fibers of fibronectin and hemidesmosomes which connect intermediate filaments to basal laminae Triggers of apoptosis Lack of survive signals Activation of death receptors Cell damage or stress DNA damage Apoptosis It causes cell shrinkage chromatin    See Answer
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