How can the peak area be used to quantitatively analyze a sample using GC?

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Chemistry

How can the peak area be used to quantitatively analyze a sampleusing GC?

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GAS CHROMATOGRAPHYBackgroundGas chromatography is a powerful means of performing qualitativeand quantitative measurements of complex mixtures of volatilesubstances In this experiment you will use gas chromatography forquantitative analysis of complex mixtures and determine parametersused to optimize the separation The experiment uses commonindustrial solvents cyclohexane C6H12methylene chloride CH2Cl2 and tolueneC2H6 They are toxic must be handled withrespect and must be disposed of in appropriate containersTheoretical PlatesThe separation process in gas chromatography can be compared toa multiple distillation or a fractional distillation using a refluxcolumn Gas chromatography uses relatively long packed or opentubular capillary columns and is subsequently far more efficient atseparation than fractional distillations with short reflux columnsIn addition gas chromatography uses packing orstationaryphases that can be liquid or solid and may exhibit an affinitytoward the compounds being separated The columnefficiency of a gas chromatography column is gauged bythenumber of theoretical plates n The conceptof a plate is a carryover from the first fractionatingcolumns which used discrete plates for separation Thechromatography column does not have discrete plates The number oftheoretical plates is the number of discrete distillations thatwould have to be performed to obtain an equivalent separation See Answer

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