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Harold is a 62 year old man who was found to be suffering from depression one...

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Medical Sciences

Harold is a 62 year old man who was found to be suffering fromdepression one year after a diagnosis of heart failure. Sertralinewas added to his current prescription of irbesartan.

a) Compare the mechanism of action and clinical effects of thesetwo drugs.

b) A move to a healthy lifestyle is recommended for people withheart failure. Discuss how the adverse effects of antidepressantmedication may interfere with this. (1 mark)

Answer & Explanation Solved by verified expert
3.8 Ratings (344 Votes)
Answer a Sertraline increases the 5 HT 5 Hydroxytryptamine monoaminergic and help against depression and Irbesartan block the Angiotensin receptor 2 and decrease the blood pressure Depression results due to Decreased monoaminergic 5 Hydroxytryptamine and Noradrenergic activity in Brain and therefore drugs increasing their activity are called Typical antidepressant and drugs acting by    See Answer
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