(h) Pseudomonas aeruginosa also usesthe Entner Doudoroff pat...

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(h) Pseudomonas aeruginosa also usesthe Entner Doudoroff pathway to de...

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H in Psudomonas auroginosa gene for phosphofructokinsase 2 pfk2 is absent which is regulatory enzymeof glycolysis and henve glucose cannot be converted into pyruvate and hence organism cannot utilised glucose as carbon source and caused death To overcome this limitation organism operates another pathway called EntnerDoudoroff ED pathway to convert glucose into pyruvate But this ED pathways produce only one ATP and one NADH and NADPH compared to 2ATP and 2NADH in glycolysis I Brucella abortus strain 19 does not operates or having functional glycolysis Pentose phosphate pathway or ED pathway and hence cannot utilised glucose as carbon source and can gro only in complex medium So key enzyme which are missing from Babortus stain 19 cold be phospho fructos kinase2 pfk2 so that glycolsis stop further glucose 6 phosphate dehydrogenase GPD is also missing which is regulatory enzyme ....

(h) Pseudomonas aeruginosa also uses the Entner-Doudoroff pathway to degrade glucose. Use IMG or BLAST (or MetaCyc)...

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