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GLUT4 is a protein channel that facilitates the transport of glucose into the cell Under...

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Biology

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GLUT4 is a protein channel that facilitates the transport of glucose into the cell Under nor mal conditions some of the GLUT4 proteins that are synthesized by the cell do not become active and are instead stored within the membranes of vesicles The insulin receptor tyrosine kinase TRK is a receptor protein that facilitates the decrease of glucose concentration in the bloodstream by increasing the uptake of glucose by cells When the insulin hormone binds the insulin TRK receptor a signal transduction pathway causes the activation and addition of GLUT4 to the cell membrane A model of this signal transduction pathway is illustrated in the figure below insulin insulin receptor cytoplasm A model of the insulin TRK receptor signal transduction pathway Which of the following best predicts the effect of a loss of function of the insulin TRK A B C D The stimulation of the signal transduction pathway will increase The concentration of glucose inside the cell will increase The storage of GLUT4 inside the cell will increase GLUT4 containing vesicle glucose The number of GLUT4 molecules in the plasma membrane will increase GLUT 4

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