Glucose are stored as glycogen in muscle cells, from which it can again be mobilized during...

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Biology

Glucose are stored as glycogen in muscle cells, from which itcan again be mobilized during exercise.
a) Write down the partial reactions as well as the net yield forthe conversion of glucose-6-phosphate to glycogen and for theconversion of glycogen to glucose-6-phosphate.
b) Calculate the energy required for the consumption of the totalprocess of converting glucose-6-phosphate to glycogen and back toglucose-6-phosphate expressed as energy-rich phosphate bonds (ATPequivalents).
Î”G0â€™ for the reaction: ATP + H2O â†’ ADP + Pi = â€“30.5 kJâˆ™mol-1.
c) Calculate Î”Gâ€™ for the reaction at 25 Â°C and pH 7, when [ATP] = 5mM, [ADP] = 0.5 mM and [Pi] = 1.0 mM.
Phosphocreatin constitutes a small extra storage of energy withinmuscle cells, and is formed from phosphorylation of creatin. Thereaction is catalyzed by creatine kinase and Î”G0â€™ for the reactionis +2.3 kJâˆ™mol-1 (progressing towared the formation ofphosphocreatin).
d) Calculate how much phosphocreatin formed relative to creatin atequilibrium in the creatin kinase catalyzed reaction (assuming thesame temperature, pH and concentrations of ATP and ADP as indicatedin the previous question).

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4.1 Ratings (821 Votes)

Answeraglucose6phosphate to glycogenGlucose6phosphate isconverted into glucose1phosphate byphosphoglucomutaseThis is followed byformation of UDPglucose UTP is reacted See Answer

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