Glomerular Filtration

1. What is the major force/pressure that causes filtration?

1. What is the major force/pressure that causes reabsorption?

1. What would happen to the filtration rate if glomerularcapillaries were damaged to an extent to be leaky to plasmaproteins?

Identifying how renal arterioles affect GFR

Complete the following table that describes how changes in thediameters of these resistance vessels affect glomerular hydrostaticpressure and GFR (assuming no change in renal arterial pressure)with no change, increase, or decrease.

Afferent Arteriole	Efferent Arteriole	Glomerular Hydrostatic Pressure and FiltrationRate
No change	No change	Normal
Constricts	No change
No change	Constricts
Dilates	No change
Dilates	Constricts

How renal arterioles respond to changes in blood pressure

Changes in mean arterial pressure (MAP) can lead to wide changesin systemic pressure, including the renal arteries. Use yourunderstanding of the renal mechanisms identified in part and yourunderstanding of cardiovascular physiology and blood pressure toanswer the following questions.

1. In the human body, if MAP is between 80 and 160mmHg, wouldGFR be expected to change as MAP changes? Explain your answer,including in your answer the afferent arteriolar response, whatstimulates it to do so (2 stimuli), and the purpose of thisresponse.

1. GFR:

1. afferent arteriole response:

1. two stimuli of response:

1. purpose of response:

2. What would happen to GFR if MAP rises above 160mmHg? Explainyour answer, including in your answer what each arteriole does,what stimulates their responses, and the purpose of theirresponses.

1. GFR:

1. afferent arteriole response:

1. efferent arteriole response:

1. stimulus for responses:

1. purpose of responses:

3. What would happen to GFR if MAP falls below 80mmHg? Explainyour answer, including in your answer what each arteriole does,what stimulates their responses, and the purpose of theirresponses.

1. GFR:

1. afferent arteriole response:

1. efferent arteriole response:

1. stimulus for responses:

1. purpose of responses: