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Gleevec is a chemotherapy drug used to treat cancer. What is the mechanism by which...

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Biology

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Gleevec is a chemotherapy drug used to treat cancer. What is the mechanism by which Gleevec blocks Abl kinase enzyme action?Gleevec reduces the ATP level in the body and starves the Abl enzymeGleevec purifies cancer cells and returns them to a normal functioning stateBinding of Gleevec to the active site locks Abl in an inactive conformationBinding of Gleevec to the active site mutates threonine 315 to methionineGleevec is a protease that cleaves the Abl protein at the regulatory spine

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