Given the expression profile of CFTR (tissues in which it is normally expressed) in non-affected individuals...

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Biology

Given the expression profile of CFTR (tissues in which it isnormally expressed) in non-affected individuals and what you knowabout CFTR function and membrane transport, how would dysfunctionalCFTR lead to each of the following common cystic fibrosis symptoms?Use proper terms and include specific information relevant tomembrane transport in your explanations.
a.Thickened mucus of the lungs, pancreas, and GI tract
b.Increased bacterial infections of the lungs
c. Poor growth and malnutrition

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CFTR Cystic Fibrosis Transmembrane Conductance Regulator gene located on the chromosome 7 encodes 1480 amino acids produces CFTR protein this protein acts as the channel on the membrane of cells associated with production of mucus saliva tears and digestive enzymes the channel helps in the transport of negatively charged particles called as the chlorine ions in and out of the cells thus helps in maintainiong the See Answer

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