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Give an account of the molecular genetic defects that underlie thalassaemia and sickle cell disease. What are the...

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Biology

Give an account of the molecular genetic defects thatunderlie
thalassaemia and sickle cell disease.
What are the resulting clinical features of these conditions?
Describe the current status and future prospects of ONE of thefollowing
genetic-based treatment options for thesehaemoglobinopathies:
(i) gamma-globin gene reactivation; (ii) gene therapy. (min500words)

Answer & Explanation Solved by verified expert
4.3 Ratings (783 Votes)
Thalassemia an inherited blood disorder in which the body makes an abnormal form of hemoglobin Hemoglobin a protein molecule in red blood cells that carries oxygen The disease results in excessive destruction of red blood cells which leads to anemia Other symptoms bone deformities especially in the    See Answer
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