For each, whether they illustrate forward, or reverse, geneticapproaches, and explain why you made that choice.
A.Your graduate student read a paper in which mutations in aspecific antioxidant gene leads to resistance to the biologicaleffects of cocaine in mice. She decides to use Cas-CRISPR to make atargeted mutation in the Drosophila homolog of this gene andexamine the effects of cocaine on the resulting mutant flies. Isthis a forward or reverse genetic approach?
B. Your graduate student has performed a genetic screen andisolated twenty mutations that lead to resistance to the drug PCPin flies. She proceeds to clone and sequence the mutated genes. Isthis a forward or reverse genetic approach?
