For each, whether they illustrate forward, or reverse, genetic approaches, and explain why you made that...

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Biology

For each, whether they illustrate forward, or reverse, geneticapproaches, and explain why you made that choice.

A.Your graduate student read a paper in which mutations in aspecific antioxidant gene leads to resistance to the biologicaleffects of cocaine in mice. She decides to use Cas-CRISPR to make atargeted mutation in the Drosophila homolog of this gene andexamine the effects of cocaine on the resulting mutant flies. Isthis a forward or reverse genetic approach?

B. Your graduate student has performed a genetic screen andisolated twenty mutations that lead to resistance to the drug PCPin flies. She proceeds to clone and sequence the mutated genes. Isthis a forward or reverse genetic approach?

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A answer This illustrate forward genetic approach because single specific antioxidant gene underlies a specific mutant phenotype is targeted to study the effects of cocaine on the    See Answer
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