For each of these 3 channels, describe where they are found, how
they work, and the...
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For each of these 3 channels, describe where they are found, howthey work, and the role they play in physiology: 1) the cardiacryanodine channel, 2) the voltage gated calcium channel on neurons,and 3) the dihydropyridine ryanodine channel
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1 Cardiac ryanodine channel Location This is a calcium ion channels found on the sarcoplasmic reticulum of the cardiac muscle This ryanodine channel or RyR helps in the cardiac muscle contraction through calcium ion release This channels are mainly located in the terminal cistern of the sarcoplasmic reticulum of cardiac muscle Mechanism of action The terminal cistern of the sarcoplasmic reticulum is the store house of the calcium ions In relax condition this this ryanodine channels are closed When action potential arrives at the T tubule the L type calcium channels in the T tubule is opened and calcium influx occure This calcium ions triggers the opening of ryanodine channels in the sarcoplasmic reticulum This opening of ryanodine cahnnels causes the release of stored calcium in the
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