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For Barbiturates answer the following: - Type of receptor it binds to. Ion channel recept or...

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Medical Sciences

For Barbiturates answer the following:

- Type of receptor it binds to. Ion channel recept or GPCRs, isit excitatory or inhibitory on postsynaptic cell.

- Identify the endogenous molecule that the drug is interactingwith and how it changes its function.

-Discuss the changing synaptic transmission by drugs based onthe neural circuits that are affected.

Answer & Explanation Solved by verified expert
4.3 Ratings (935 Votes)
Barbiturates are classof drug which are potential allosteric modulators It also can actas GABA receptor agonist which is the principal inhibitoryneurotransmitter in CNS The principle receptor for barbituratesare GABA receptors on which it binds at multiplehomologous transmembrane pockets of subunit interface    See Answer
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