For a study, 375 patients were randomly assigned tor eceive adaily dose of levvofloxacin, and 363 were given placebo. In thegroup receiving treatment, fever was present in 243 patients forthe duration of neutroenia, whereas feverw as experienced by 308patients in the placebo group. Using this information, determinewhether or not the proportion of patients with fever differedbetween the two groups at the 1% level of significance. State thenull and alternative hypothesis, manually calculate the teststatistic and determine its p-value. Then state your decision andconclusion.