FIVE CLINICAL CHEMISTRY QUESTIONS: 1. What is the origin of AFP in the amniotic fluid? When...

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Chemistry

FIVE CLINICAL CHEMISTRY QUESTIONS:
1. What is the origin of AFP in the amniotic fluid? When do AFPlevels peak in amniotic fluid? In maternal circulation? When shouldmaternal blood levels be drawn?
2. What other test performed on amniotic fluid may confirm thediagnosis of a NTD? What values (elevated, decreased) will thisassay take if a NTD is present?
3. Describe the delta O.D. spectrophotometric test for amnioticfluid bilirubin and discuss the clinical significance of abnormalresults. (Include a description of Hemolytic Disease of theNewborn)
4. Briefly describe the changes in lipid composition of amnioticfluid before and during fetal lung maturation.
5. Describe the triple marker screen for Down syndrome and theexpected changes from normal values for each in an affectedpregnancy.

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1 What is the origin of AFP in the amniotic fluid When do AFP levels peak in amniotic fluid In maternal circulation When should maternal blood levels be drawn Alphafetoprotein AFP fetoprotein likewise now and then called alpha1fetoprotein alphafetoglobulin or alpha fetal protein is a protein that in people is encoded by the AFP gene The AFP gene is situated on the q arm of chromosome 4 4q25 AFP is a noteworthy plasma protein delivered by the yolk sac and the liver amid fetal improvement It is thought to be the fetal type of serum egg whites AFP ties to copper nickel unsaturated fats and bilirubin and is found in monomeric dimeric and trimeric formsAFP is the most rich plasma protein found in the human hatchling Plasma levels diminish quickly after birth yet start diminishing prenatally beginning toward the end of the main See Answer

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