Fill in the blank- During eukaryotic transcription, the assembly of the general transcription factors begins with...

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Biology

Fill in the blank- During eukaryotic transcription, the assemblyof the general transcription factors begins with the binding of thefactor____in a complex with the general transcriptionfactor_to DNA, causing a marked local distortion in thedouble helix. This factor binds at the DNA sequence calledthebox, which is typically located 25 nucleotides upstreamfrom the transcription start site. Once RNA polymerase II has beenbrought to the promoter DNA, it must be released to begin makingtranscripts. This release process is facilitated by the addition ofphosphate groups to the tail of RNA polymerase by thefactor_. General transcription factor and RNA polymerase arenot sufficient to efficiently initiate transcription in the celland are affected by proteins bound thousands of nucleotides awayfrom the promoter. Proteins that link distantly bound transcriptionregulators to RNA polymerase and the general transcription factorsinclude the large complex of proteins called the _. Thepackaging of DNA into chromatin also affects transcriptionalinitiation, and histone__ is an enzyme that can render theDNA less accessible to the general transcription factors.

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Transcription factor II D TFIID is a general transcription factor that helps regulate gene expression and is a part of the RNA polymerase II preinitiation complex in the eukaryotic transcription process This TFIID is the one that first recognizes the TATA element and TATAbinding protein TBP is a part of TFIID and is also a general transcription factor that binds to the TATA box DNA sequence usually present upstream of the initiator box sequence The Transcription Factor IIH is a transcription See Answer

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