Explain why the neocortex is not able to function as an index by following the indexing...

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Medical Sciences

Explain why the neocortex is not able to function as an index byfollowing the indexing theory, give 3 reasons (hint: hippocampusindexing theory is a better fit)
If NMDA receptors get knocked out of the hippocampus area, whatwill be the impact on both pattern completion and patternseparation according to the index theory?

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CORTICAL ORGANIZATION The neocortex is generally arranged in six layers The most common neuronal type is the pyramidal cell with an extensive vertical dendritic tree that may reach to the cortical surface Their cell bodies can be found in all cortical layers except layer I The axons of these cells usually give off recurrent collaterals that turn back and synapse on the superficial portions of the dendritic trees Afferents from the specific nuclei of the thalamus terminate primarily in cortical layer IV whereas the nonspecific afferents are distributed to layers IIV Pyramidal neurons are the only projection neurons of the cortex and they are excitatory neurons that release glutamate at their terminals The other cortical cell types are local circuit neurons interneurons which have been classified based on their shape pattern of projection and neurotransmitter Inhibitory interneurons basket cells and chandelier cells release GABA as their neurotransmitter Basket cells have long axonal endings that surround the soma of pyramidal neurons they account for most inhibitory synapses on the pyramidal soma and See Answer

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