Explain why the mutation of Asp-52 to Asn-52 decreases enzyme activity of lysozymes by 10,000 fold.

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Chemistry

Explain why the mutation of Asp-52 to Asn-52 decreases enzymeactivity of lysozymes by 10,000 fold.

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The active site of lysozyme has Asp52 and Glu35 as the catalytic residues During catalysis glutamic acid residue transfers a proton to the substrate to form an oxonium ion    See Answer
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