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Explain the role of ubiquitination in the regulation of cellular protein levels.

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Biology

Explain the role of ubiquitination in the regulation of cellularprotein levels.

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Ubiquitination is a 76amino acid protein that can be ubiquitously expressed in all tissues Its function is ligating Ub molecules to a substrate protein thereby regulating protein stability and translocation It can be considered as one of the most common forms of post translational protein modification Ubiquitination requires ATP and involves three enzymatic reactions requiring E1 E2 and E3 ligases In this process E3 ligase conjugates Ub to lysine K residues of the    See Answer
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