Explain the initiation and regulation of labor contraction including all organs and hormones (and hormone-like molecules)...

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Medical Sciences

Explain the initiation and regulation of labor contractionincluding all organs and hormones (and hormone-like molecules) thatparticipate in the process. Describe the positive feedbackmechanism of labor contractions. Why do you think the slowintravenous injection of synthetic oxytocin (Pitocin®) can be usedto induce parturition (childbirth)? After childbirth,pituitary-derived oxytocin also triggers milk ejection. What is theinitial stimulus for the secretion of oxytocin? What is the targetcell type of oxytocin in the mammary gland? For parturition, whichlayer of the uterus does this hormone act on?

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Ans Initiation and regulation of labour The exact sequence of events that leads to uterine contractions is still largely unknown Some studies suggest mechanical stretch and hormones work together to initiate contractions in normal laborHowever due to the role of inflammation in preterm labor other studies suggest that inflammatory mediators such as cytokines and prostaglandins initiate uterine contractions Mechanical stretch Mechanical stretch refers to tension on myometrial cells as the uterus distends The physical stretching of the uterus causes an influx of ions namely sodium and    See Answer
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