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Explain the general mechanism for the simultaneous transport of Na+ and K+ by the Na+/K+ ATPase...

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Biology

Explain the general mechanism for the simultaneous transportof Na+ and K+ by the Na+/K+ ATPase (aka. Na+/K+ pump)describing:
The result of this transport on the concentrations of Na+ andK+ inside and outside of the cell
How the binding of Na+ and K+ are related to the conformationchanges on the protein
We discussed F-type pumps, which can also function in thereverse direction (i.e. ATP synthase). Explain how this protein canfunction both as a pump and as a \"channel-like protein\" (althoughthe mechanism of proton transport is not the same as a typicalchannel) depending on the direction in which protons move (down oragainst their free energy gradient). How is ATP hydrolysis orsynthesis associated to the movement of protons in each case?
Explain why the cystic fibrosis conductance regulator (CFTR)does not function as a pump even though it is a member of the ABCtransporter family (what type of protein does CFTR behavelike?)

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