Explain how impaired or reduced renal function has the potential to impact the functionality of the...

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Explain how impaired or reduced renal function has the potentialto impact the functionality of the cardiovascular system?

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kidney functions as a sensory organ that is richly innervatedwith chemoreceptors and baroreceptors These renal afferent nervesconnect with centers in the brain that regulate blood pressure andcentral sympathetic outflow Animal studies have highlighted theimportance of the renal afferent nerves in the pathogenesis of SNSoveractivity and high blood pressure in renal failure In 56thnephrectomized rats the increase in blood pressure was accompaniedby increased NE turnover in the areas of the brain responsible forsympathetic regulation including the posterior anterior andlateral hypothalamic nuclei and the locus ceruleus In animalmodels selective renal afferent See Answer

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