Exhibit L.1 reports the multivariate odds ratios comparing each category to women who never had an...

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Exhibit L.1 reports the multivariate odds ratios comparing eachcategory to women who never had an induced abortion and had atleast one pregnancy. Researchers were able to interview 845 out of1,011 (83.5 percent) of the eligible cases and 961 out of 1,239 (78per- cent) of the eligible controls. Of the cases, only 689 (81.5percent) had complete information on abortion history, compared to781 (81.3 per- cent) of the eligible controls.

Abortion History

Cases

Controls

Crude OR2

Multivariate OR (95% CI)3

Ever had abortion

210

201

1.5 (1.2–1.9)

1 abortion only

150

142

1.5 (1.1–2.0)

2+ abortions

60

59

1.6 (1.0–2.4)

Age at first abortion

<18

20

15

2.5 (1.1–5.7)

18–19

34

36

1.7 (1.0–3.0)

20–29

115

123

1.3 (1.0–1.7)

30+

41

27

2.1 (1.2–3.5)

Timing of first abortion

Before 1st birth

69

76

1.4 (1.0–2.0)

After 1st birth

74

63

1.5 (1.0–2.2)

Never gave birth

67

62

1.7 (1.2–2.6)

Never had abortion

479

580

––

Never had an abortion and at least onepregnancy1

466

564

––

Note: 1. Estimated from the data. 2. Multivariate ORadjusts for age, family history of breast cancer, religion, age atfirst pregnancy. 3. Both crude and multivariate odds ratioestimates risk relative to women with a least one pregnancy whonever had an induced abortion. Source: Daling et al.(1994).

Calculate the crude odds ratios for each of the abortion historystrata in Exhibit L.1. What is the overall increased risk ofabortion after adjusting for several covariates?

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