Etanercept is a TNF-α antagonist composed of the dimeric fusion protein of extracellular ligand-binding portion of...
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Etanercept is a TNF-α antagonist composed of the dimeric fusionprotein of extracellular ligand-binding portion of the soluble75-kDa TNF-α receptor II and the fragment-crystallisable (Fc)portion of human immunoglobulin (IgG).†Based on this quote, whatdoes etanercept compete with? Where does etanercept and itscompetitor bind?
Etanercept is a TNF-α antagonist composed of the dimeric fusionprotein of extracellular ligand-binding portion of the soluble75-kDa TNF-α receptor II and the fragment-crystallisable (Fc)portion of human immunoglobulin (IgG).†Based on this quote, whatdoes etanercept compete with? Where does etanercept and itscompetitor bind?
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ANSWER Etanercept is a soluble p75 TNFalpha receptor fusion protein that binds TNFalpha and has a longer half life than the native soluble receptorEtanercept a fully soluble human dimeric fusion protein functions as a TNF inhibitor by
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