Endocrine Case Study A 54-year old man finally goes to the doctor at the urging of his...

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Endocrine Case Study
A 54-year old man finally goes to the doctor at the urging ofhis wife. His face, neck and shoulders have become puffy while hislimbs are thinning. He believes he is in good shape because all hisfriends are gaining weight while heâ€™s just shifting his around. Heclaims to eat a relatively healthy diet and has no allergies orother health problems. Heâ€™s not sure why his arms and legs seem tobe getting thinner, even though he still does a lot of yard workaround the house, but he hasnâ€™t felt as strong lately (â€œbut hey,Iâ€™m 54â€). On observation, he has a pulse of 65 bpm and a bloodpressure of 150/95. The only other â€œdifferentâ€ things heâ€™s noticedis that he seems to be bruising more easily than usual.
The patient takes no medications other than an occasional doseof ibuprofen. The patient went to the hospital for a blood draw andtest the next morning. The results are:
Plasma ACTH = 120 pg/mL Plasma cortisol = 35 mcg/dL Serum TSH = 3.3mcU/mL Serum aldosterone = 18 ng/dL Serum insulin = 35 mcU/mL SerumT4 = 1.4 ng/dL Plasma glucose = 185 ng/dL Hemoglobin A1c = 5.5%
Diagnosis:
What is the evidence of Diagnosis:

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Diagnosis The level of cortisol in the blood is increased Serum aldosterone levels increased Plasma glucose level decreased due to dec in insulin Patient is suffering from Cushings syndrome Signs and symptoms of Cushings syndrome vary People who have very high levels of cortisol for a long time are likely to have clear signs of the disorder including weight gain thin arms and legs a round face increased fat around the base See Answer

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