Duncan is a Caucasian male (age 14) that is brought to your attention because his family...

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Biology

Duncan is a Caucasian male (age 14) that is brought to yourattention because his family concerned about his inability toperform strenuous exercise. Duncan suffered severe muscle crampingduring his P.E. classes but is normal if at doing routine physicalactivity or performing light to moderate exercise. A physicalexamination showed poorly developed muscle tissue, but his liversize was normal. A fasting glucose level check showed normallevels.
You suspect that Duncan is suffering from a glycogen metabolismrelated disease and check his response to glucagon. You inject himwith a large dose of the hormone and measure the glucose levels inhis blood. After the injection, Duncanâ€™s blood glucose levels rosesharply.
Why did you perform this test?
Is Duncanâ€™s glucagon response what youwould expect in a normal person? Explain briefly
To further investigate you analyze biopsies of Duncanâ€™s muscleand liver. Although the structure of the glycogen in both tissuesappear to be normal, there is an elevation in the glycogen level inthe muscle tissue, while that in the liver is within normalrange.
What is a hypothesis regardingDuncanâ€™s condition?

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4.1 Ratings (858 Votes)

Background informationGlycogen stores in muscle and liver The liver converts itsstored glycogen to glucose when the blood level of glucosedecreases while muscle converts when the requirement of ATPincreases Therefore the storage level of glycogen in these twovaries depending upon the demand of the bodyGlucagon is the hormone See Answer

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