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DOWN SYNDROME What is the history of the disease? How common is it, and how is it...

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Medical Sciences

DOWN SYNDROME
What is the history of the disease?
How common is it, and how is it diagnosed?
What are the major signs, symptoms?
What techniques sre used for genetic screening of thedisease?

Answer & Explanation Solved by verified expert
3.8 Ratings (519 Votes)
Down syndrome is a chromosomal disorder in which there is an extra chromosome 21 47 XY 21 or 47 XX 21 It is also known as trisomy 21 or mongolism A child with Down syndrome has severe physical and mental growth retardation Down syndrome is named after a British physician Dr John Langdon Down who discovered this disorder and described its features Overall it affects 1 in 1000 live births annually The incidence is more with increased maternal age commonly above 35 years of age incidence at 35 years of maternal age 1270 at 40 years 1100 at 45 years 150 It is diagnosed    See Answer
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